Cancer patient molecular profiling for precision medicine using Novigenix LITOseek platform
Samples
Use of data and sample
Breast Cancer
Triple negative Breast Cancer – SPECTA localized disease
Colorectal Cancer
Colorectal cancer – SPECTA | Colorectal Cancer – Leuven cohort | Colorectal Cancer – CLB cohort | Colorectal Cancer – Saint-Luc cohort
Head and Neck Cancer
Squamous Cell Carcinoma of the Head and Neck Cancer – SPECTA
Objective(s) of the research
Analyze and integrate molecular data of cancer patients for the identification of predictive biomarkers of response to current therapies, resistance mechanisms and discovery and validation of novel therapeutic targets.
Impact of the research
Actionable predictive biomarkers of response will enable clinicians make informed decisions for patient stratification, thereby offering to patients therapies that most likely benefit from. Moreover, discovery and validation of novel therapeutic targets will pave the way to the development of new therapeutic agents to treat those patients that are resistant to current available therapies. Altogether, this project has the potential to improve patient care and quality of life.